"Mayfair is one of the most luxurious areas in London," explained the hotel's duty manager Matteo Flamigni.
"Oscar Wilde used to revel in this street, which is named after the local pub - The Half Moon House. This is where the bachelors came to party so there are lots of nods to dandies around the hotel.
"We have a range of stylish rooms and suites that cater for various types of people that are all unique in their own way. We want to become known as the best townhouse in London."
Rooms start at £252 a night, suites from £660 and signature suites from £2,340 - all rooms only for two people. Visit the Mayfair Townhouse website here for more booking information.