Visitors to the Dudley attraction between March 28 and April 14 will be invited to learn about, and take part in, traditional cleaning methods, from washing windows with newspaper and vinegar to washing clothes in a dolly tub.
There will also be Spring Cleaning-themed street games where young and old can gather in the main village to race against each other, competing in Team Speed Hanging, The Sock Throw and the Mop Head Marathon. Creative visitors can even make peg dolls and peg planes in a series of free craft activities taking place every day from 11am till 3pm.
The museum in Tipton Road was established in 1975, with the first buildings moved to the site in 1976. It now covers 26 acres and boasts an entire recreated village, two mine shafts, a limekiln, a stretch of canal and a working replica of the world's first steam engine.
You can also take a trip on a tram, have a pint at the mid-19th century Bottle and Glass Inn and enjoy fish and chips cooked in beef dripping at the 1930s Hobbs' chippy.
Many people will have seen the museum in the comfort of their own homes. It has been used in many television dramas and films, the most recent being WPC 56, screened daily for a week on BBC 1 at 2.15pm.