"I love the fact that you can shape the entire evening by thinking on your feet," says O'Briain. "If Plan A doesn't work, you have to come up with Plan B immediately."
"It's like walking a tightrope," adds the comic. "The audience love it because they can see you've got nothing up your sleeve and that things could very easily go wrong. They realise that this could go anywhere. You're not given any easy ride." He adds: "Everyone has something to give me."
"When I'm questioning the audience, my stance is not, 'How can I mock this person?' It's, 'I am an eight-year-old meeting this person for the first time. What aspects of them do I want to talk and enthuse about?'"
Dara O'Briain, a 42-year-old father-of-two, has become as synonmous with Star Gazing Live as comedy shows, but after all, he did graduate from University College Dublin in mathematics and theoretical physics.
"It's great to tackle subjects that are more thought-provoking," says O'Briain, "but I have this dread that people will go, 'Oh Dara's show – there'll be some bit where he bores us with some science thing'."
"When you arrive at an empty theatre, the potential is immense," explains O'Briain. "You think, 'This is going to be magical."
He adds: "The other day, I sat in an empty theatre thinking, 'I just love these rooms'. I'm on the board of the Theatres Trust in order to protect these wonderful buildings. It's not about NIMBY-ism; it's because I adore these places. It still gives me such a thrill to walk on stage."
"I hope they're unable to talk because I beaten them over the head with so much humour and punched them repeatedly in the face with jokes – that's my aim!" he laughs.
"I want them spent. I want them silently driving back home absorbing it all, while I'm left in the empty theatre quietly wiping the make-up off my face in a mirror surrounded by light bulbs."
Dara O Briain - Crowd Tickler UK Tour
Tickets cost from £23 via the Dara O'Briain website.
15 - 17 Oct 2015 - London Eventim Apollo
0844 249 4300
20 Oct 2015 - Ipswich - Regent Theatre
01473 433 100
21 Oct 2015 - Brighton - Dome
01273 709 709
23 Oct 2015 - Oxford New Theatre
0844 871 3020
24 - 25 Oct 2015 - Cardiff - St David's Hall
029 2087 8444
27 - 28 Oct 2015 - Sheffield City Hall
0114 278 9789
29 - 30 Oct 2015 - Douglas, Isle of Man - Villa Marina
01624 694 555
3 Nov 2015 - Hull City Hall
4 Nov 2015 - Halifax, Victoria Theatre
5 Nov and 7 Nov 2015 - York Barbican Theatre
0844 854 2757
6 Nov 2015 - Bradford St George's Hall
12 - 14 Nov 2015 - Birmingham Hippodrome
0844 338 5000 or from the Birmingham Hippodrome website.
19 - 22 Nov 2015 - Vicar Street, Dublin,
27 Nov 2015 - Swansea Grand Theatre
28 Nov 2015 - Plymouth Pavilions
0845 146 1460