The free event takes place from 4 - 6 October and will entertain audiences of all ages with dance, music, theatre and other exciting activities.
Galleries, bars, cafes, cultural venues and outdoor public spaces across Digbeth and in Southside will host events during Birmingham Weekender, which is produced by Culture Central.
A detailed programme is set to be revealed by the end of summer to match the previous lively festivals in 2017 and 2015.
Emily Labhart, Producer of Birmingham Weekender said: "The festival is a huge celebration of the dynamic arts and cultural scene in the city. It presents the perfect opportunity to showcase the artists and organisations that work year-round to make great things happen for the people of Birmingham.
"With everything from exhibitions to workshops, to performances through to walking tours - I can't wait for us to shine a spotlight on this part of the Birmingham."
The previous festival included vibrant theatrical events